Tyrosine hydroxylase (TH) is a crucial enzyme that plays a rate-limiting role in the biosynthesis of catecholaminergic neurotransmitters in mammals. It primarily catalyzes the conversion of L-tyrosine into 3,4-dihydroxyphenylalanine (DOPA), which is subsequently synthesized into bioactive substances such as dopamine, norepinephrine, and epinephrine. TH utilizes tetrahydrobiopterin as a cofactor and requires Fe2+ as an essential activator. It is abundantly distributed in dopaminergic and noradrenergic neurons. Not only does TH contribute to improving skin condition, regulating emotions, and boosting immunity, but it also promotes the secretion of 5-hydroxytryptamine, thereby enhancing sleep quality. Its specific spatial structure enables it to bind substrates and catalyze oxidation reactions, thereby exerting multiple crucial functions within the biological system. In summary, tyrosine hydroxylase plays an indispensable role in maintaining normal physiological functions in the human body.
Human tyrosine hydroxylase,TH ELISA Kit
Validated Data
Code:CSB-E09661h
Size:96T/48T
Sensitivity:0.078 ng/mL
Detection Range:0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following TH reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TH Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA154990 | Phospho-TH (Ser40) Antibody |
Human,Mouse,Rat | ELISA,IF |
CSB-PA439504 | Phospho-TH (Ser19) Antibody |
Rat | ELISA,IF |
CSB-PA695636 | TH (Ab-31) Antibody |
Mouse,Rat | ELISA,WB |
CSB-PA000731 | Phospho-TH (S19) Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA004284 | TH Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA004285 | TH Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA050254 | Phospho-TH (S62) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA050255 | TH Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA011030 | Phospho-TH (S71) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA195276 | TH Antibody |
Human | ELISA,IHC |
CSB-PA903853 | TH Antibody |
Human | ELISA,IHC |
CSB-PA023470LA01HU | TH Antibody |
Human, Mouse, Rat | ELISA, WB, IHC |
CSB-PA023470LB01HU | TH Antibody, HRP conjugated |
Human | ELISA |
CSB-PA023470LC01HU | TH Antibody, FITC conjugated |
Human | |
CSB-PA023470LD01HU | TH Antibody, Biotin conjugated |
Human | ELISA |
TH Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004286 | TH Antibody |
Rat | WB, IHC, ELISA |
CSB-PA006345 | Phospho-TH (S8) Antibody |
Rat | WB, IHC, ELISA |
TH Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023470HU CSB-EP023470HU CSB-BP023470HU CSB-MP023470HU CSB-EP023470HU-B |
Recombinant Human Tyrosine 3-monooxygenase (TH) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TH ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E09661h | Human tyrosine hydroxylase,TH ELISA Kit |
serum, plasma, tissue homogenates | 0.078 ng/mL |