TMEM37

TMEM37, also known as Transmembrane Protein 37, is a protein associated with various cellular functions. It is predicted to enable calcium channel activity and voltage-gated ion channel activity, playing a role in calcium ion transmembrane transport and regulation of ion transmembrane transport. TMEM37 is also integral to the membrane structure. Its expression is observed in multiple tissues, including the kidney and fat. Diseases associated with TMEM37 include schizophrenia and necatoriasis. In terms of drug development, TMEM37 has been identified as a potential target for therapeutic antibody development, with pre-made monoclonal antibodies available for research and drug discovery.

Recent research has highlighted TMEM37's involvement in several signaling pathways, including those related to calcium signaling and ion transport. This has opened up avenues for potential therapeutic interventions. While the exact role of TMEM37 in disease pathogenesis is still being elucidated, its potential as a biomarker and therapeutic target has garnered significant interest in the pharmaceutical industry.