TNFSF13B, a member of the tumor necrosis factor superfamily 13B, also known as BLyS, BAFF, and TALL-1, is a cytokine mainly produced by B cells. It is crucial for B cell maturation and survival. TNFSF13B's mechanism of action involves binding to its receptor BAFF-R, activating downstream signaling pathways like NF-κB and JAK/STAT, which promote B cell proliferation and differentiation. This factor is involved in B cell development, autoimmune disease occurrence, and tumor growth. Abnormal TNFSF13B expression is associated with B-cell related disorders such as systemic lupus erythematosus, rheumatoid arthritis, and certain types of non-Hodgkin's lymphoma.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFSF13B Antibody (CSB-PA981923)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: K562 cells, 231 cells, SKOV3 cells, Primary antibody: CSB-PA981923(TNFSF13B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
The following TNFSF13B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFSF13B Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA023990GA01HU | TNFSF13B Antibody | Human | ELISA,WB |
CSB-PA05767A0Rb | TNFSF13B Antibody | Human | ELISA |
CSB-PA897523ESR2HU | TNFSF13B Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA005018 | TNFSF13B Antibody | Human,Mouse | WB, ELISA |
CSB-PA981923 | TNFSF13B Antibody | Human | ELISA,WB,IHC |
CSB-PA108957 | TNFSF13B Antibody | Human | ELISA,IHC |
TNFSF13B Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP894359MO CSB-EP894359MO CSB-BP894359MO CSB-MP894359MO CSB-EP894359MO-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 13B (Tnfsf13b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF13B Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP897523HU CSB-BP897523HU CSB-MP897523HU CSB-EP897523HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP897523HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B), partial | E.coli |
CSB-AP002191HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | E.Coli |
CSB-MP897523HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | Mammalian cell |
CSB-MP897523HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial,Biotinylated (Active) | Mammalian cell |
TNFSF13B ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E11912h | Human B cell activation factor,BAFF ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |