TRMT12

TRMT12, also known as tRNA methyltransferase 12, is a protein - coding gene. It methylates specific positions on transfer RNAs (tRNAs), a crucial modification that affects tRNA structure and function. This protein is involved in the normal translation process of cells, ensuring the accuracy and efficiency of protein synthesis. It participates in the tRNA - related signaling pathway which is fundamental for maintaining cellular homeostasis.
Dysregulation of TRMT12 has been associated with certain genetic disorders and cancers. For instance, abnormal expression may disrupt normal cell growth and division. Currently, research on drugs targeting TRMT12 is in the early stages, focusing on understanding its detailed mechanisms to develop effective therapeutic strategies.