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Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
The following USP16 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
USP16 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA025706GA01HU | USP16 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA006653 | USP16 Antibody |
Human,Mouse,Rat | WB, ELISA |
USP16 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA025706XA01DIL | usp16 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
USP16 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP025706DIL CSB-EP025706DIL CSB-BP025706DIL CSB-MP025706DIL CSB-EP025706DIL-B |
Recombinant Danio rerio Ubiquitin carboxyl-terminal hydrolase 16 (usp16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP604362XBF CSB-EP604362XBF CSB-BP604362XBF CSB-MP604362XBF CSB-EP604362XBF-B |
Recombinant Xenopus tropicalis Ubiquitin carboxyl-terminal hydrolase 16 (usp16) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP642537RA CSB-EP642537RA CSB-BP642537RA CSB-MP642537RA CSB-EP642537RA-B |
Recombinant Rat Ubiquitin carboxyl-terminal hydrolase 16 (Usp16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP683972MOV CSB-EP683972MOV CSB-BP683972MOV CSB-MP683972MOV CSB-EP683972MOV-B |
Recombinant Macaca fascicularis Ubiquitin carboxyl-terminal hydrolase 16 (USP16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP754225XBE CSB-EP754225XBE CSB-BP754225XBE CSB-MP754225XBE CSB-EP754225XBE-B |
Recombinant Xenopus laevis Ubiquitin carboxyl-terminal hydrolase 16 (usp16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP859553MO CSB-EP859553MO CSB-BP859553MO CSB-MP859553MO CSB-EP859553MO-B |
Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase 16 (Usp16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP16 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP896915HU CSB-EP896915HU CSB-BP896915HU CSB-MP896915HU CSB-EP896915HU-B |
Recombinant Human Ubiquitin carboxyl-terminal hydrolase 16 (USP16), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
