VDAC2, also known as Voltage-Dependent Anion Channel 2, is a mitochondrial outer membrane protein. It is also commonly called Porin 2. VDAC2 plays a crucial role in regulating the transport of metabolites and ions across the mitochondrial outer membrane. It is involved in the apoptosis signaling pathway, acting as a gatekeeper to control the release of apoptotic factors from mitochondria.
Dysregulation of VDAC2 has been linked to various diseases, such as cancer and neurodegenerative disorders. In cancer, abnormal VDAC2 expression can contribute to tumor cell survival and resistance to chemotherapy. Currently, researchers are exploring VDAC2 as a potential target for drug development to disrupt cancer cell metabolism and induce apoptosis.
VDAC2 Antibody (CSB-PA025824LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA025824LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA025824LA01HU at dilution of 1:100
The following VDAC2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
VDAC2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025824GA01HU | VDAC2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA025824LA01HU | VDAC2 Antibody | Human | ELISA, IHC |
CSB-PA025824LB01HU | VDAC2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA025824LC01HU | VDAC2 Antibody, FITC conjugated | Human |
VDAC2 Antibodies for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA861818XA01DOA | VDAC2 Antibody | Arabidopsis thaliana | ELISA, WB (ensure identification of antigen) |
VDAC2 Antibodies for Oryza sativa subsp. japonica (Rice)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA743687XA01OFG | VDAC2 Antibody | Oryza sativa subsp. japonica (Rice) | ELISA, WB (ensure identification of antigen) |
VDAC2 Proteins for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Source |
---|---|---|
CSB-YP025824RB CSB-EP025824RB CSB-BP025824RB CSB-MP025824RB CSB-EP025824RB-B |
Recombinant Rabbit Non-selective voltage-gated ion channel VDAC2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Oryza sativa subsp. japonica (Rice)
Code | Product Name | Source |
---|---|---|
CSB-YP743687OFG CSB-EP743687OFG CSB-BP743687OFG CSB-MP743687OFG CSB-EP743687OFG-B |
Recombinant Oryza sativa subsp. japonica Mitochondrial outer membrane protein porin 2 (VDAC2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Source |
---|---|---|
CSB-YP861818DOA CSB-EP861818DOA CSB-BP861818DOA CSB-MP861818DOA CSB-EP861818DOA-B |
Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 2 (VDAC2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-EP723359MO CSB-BP723359MO CSB-MP723359MO CSB-EP723359MO-B |
Recombinant Mouse Voltage-dependent anion-selective channel protein 2 (Vdac2), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP882001PI CSB-EP882001PI CSB-BP882001PI CSB-MP882001PI CSB-EP882001PI-B |
Recombinant Pig Voltage-dependent anion-selective channel protein 2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP025824BO CSB-EP025824BO CSB-BP025824BO CSB-MP025824BO CSB-EP025824BO-B |
Recombinant Bovine Voltage-dependent anion-selective channel protein 2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP025824HU CSB-EP025824HU CSB-BP025824HU CSB-MP025824HU CSB-EP025824HU-B |
Recombinant Human Voltage-dependent anion-selective channel protein 2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP025824XBE CSB-EP025824XBE CSB-BP025824XBE CSB-MP025824XBE CSB-EP025824XBE-B |
Recombinant Xenopus laevis Voltage-dependent anion-selective channel protein 2 (vdac2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Meleagris gallopavo (Wild turkey)
Code | Product Name | Source |
---|---|---|
CSB-YP025824MQV CSB-EP025824MQV CSB-BP025824MQV CSB-MP025824MQV CSB-EP025824MQV-B |
Recombinant Meleagris gallopavo Voltage-dependent anion-selective channel protein 2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP025824RA CSB-EP025824RA CSB-BP025824RA CSB-MP025824RA CSB-EP025824RA-B |
Recombinant Rat Voltage-dependent anion-selective channel protein 2 (Vdac2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDAC2 Proteins for Mesocricetus auratus (Golden hamster)
Code | Product Name | Source |
---|---|---|
CSB-YP025824MRG CSB-EP025824MRG CSB-BP025824MRG CSB-MP025824MRG CSB-EP025824MRG-B |
Recombinant Mesocricetus auratus Voltage-dependent anion-selective channel protein 2 (VDAC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |