VGLL1, also known as Vestigial Like Family Member 1, is a protein coding gene that plays a crucial role in various biological processes. It acts as a co-activator for TEAD transcription factors, influencing gene expression and cell signaling. VGLL1 is involved in the Hippo signaling pathway, which regulates cell proliferation, differentiation, and apoptosis. Its dysregulation is associated with several diseases, including cancer, where it promotes tumor growth and resistance to endocrine therapies. Recent research has identified VGLL1 as a potential therapeutic target, with ongoing drug development focusing on inhibiting its activity to treat cancer and other diseases.
VGLL1 Antibody (CSB-PA858733LA01HU)
Validated Data
IHC image of CSB-PA858733LA01HU diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA858733LA01HU diluted at 1:300 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
The following VGLL1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
VGLL1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025848GA01HU | VGLL1 Antibody | Human | ELISA,WB,IHC |
CSB-PA858733XA01HU | VGLL1 Antibody | Homo sapiens (Human) | ELISA, WB (ensure identification of antigen) |
CSB-PA858733LA01HU | VGLL1 Antibody | Human | ELISA, IHC |
CSB-PA858733LB01HU | VGLL1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA858733LC01HU | VGLL1 Antibody, FITC conjugated | Human | |
CSB-PA858733LD01HU | VGLL1 Antibody, Biotin conjugated | Human | ELISA |
VGLL1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP858733HU CSB-EP858733HU CSB-BP858733HU CSB-MP858733HU CSB-EP858733HU-B |
Recombinant Human Transcription cofactor vestigial-like protein 1 (VGLL1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |