Vacuolar protein sorting-associated protein 35 is a protein in humans that is encoded by VPS35 gene. Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC.
The following VPS35 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
VPS35 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA088155 | VPS35 Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA076908 | VPS35 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA839401ESR2HU | VPS35 Antibody |
Human | ELISA, IHC |
VPS35 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025904XA01SVG | VPS35 Antibody |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ELISA, WB (ensure identification of antigen) |
VPS35 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025904XA01SXV | vps35 Antibody |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ELISA, WB (ensure identification of antigen) |
VPS35 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Source |
---|---|---|
CSB-YP025904SVG CSB-EP025904SVG CSB-BP025904SVG CSB-MP025904SVG CSB-EP025904SVG-B |
Recombinant Saccharomyces cerevisiae Vacuolar protein sorting-associated protein 35 (VPS35), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS35 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Code | Product Name | Source |
---|---|---|
CSB-YP025904SXV CSB-EP025904SXV CSB-BP025904SXV CSB-MP025904SXV CSB-EP025904SXV-B |
Recombinant Schizosaccharomyces pombe Vacuolar protein sorting-associated protein 35 (vps35), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS35 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP642243BO CSB-EP642243BO CSB-BP642243BO CSB-MP642243BO CSB-EP642243BO-B |
Recombinant Bovine Vacuolar protein sorting-associated protein 35 (VPS35), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS35 Proteins for Dictyostelium discoideum (Slime mold)
Code | Product Name | Source |
---|---|---|
CSB-YP681538DKK CSB-EP681538DKK CSB-BP681538DKK CSB-MP681538DKK CSB-EP681538DKK-B |
Recombinant Dictyostelium discoideum Vacuolar sorting protein 35 (vps35), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS35 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP839401HU CSB-BP839401HU CSB-MP839401HU CSB-EP839401HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 35 (VPS35) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP839401HU | Recombinant Human Vacuolar protein sorting-associated protein 35 (VPS35) |
E.coli |
CSB-BP839401HUd8 | Recombinant Human Vacuolar protein sorting-associated protein 35 (VPS35) |
Baculovirus |
VPS35 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP863646MO CSB-EP863646MO CSB-BP863646MO CSB-MP863646MO CSB-EP863646MO-B |
Recombinant Mouse Vacuolar protein sorting-associated protein 35 (Vps35) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |