YTHDF2

YTHDF2, also known as DF2, CAHL, HGRG8, and NY-REN-2, is a member of the YTH domain superfamily, containing the YTH domain, which is typically located in the middle of the protein sequence and binds to RNA. YTHDF2 regulates the stability and translation efficiency of mRNA by recognizing and binding to N6-methyladenosine (m6A) modified mRNA. YTHDF2 plays a crucial role in gene expression regulation, mRNA metabolism, and cellular signaling. Abnormalities in YTHDF2 function are associated with various diseases, including acute myeloid leukemia, retinitis pigmentosa, and Wilms tumor.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

YTHDF2 Antibody (CSB-PA896902LA01HU)

Validated Data

Western Blot
Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate
All lanes: YTHDF2 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 63, 57 kDa
Observed band size: 63, 50 kDa

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA896902LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA896902LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA896902LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following YTHDF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

YTHDF2 Antibodies

YTHDF2 Proteins

YTHDF2 Antibodies

YTHDF2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA896902LA01HU	YTHDF2 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA896902LB01HU	YTHDF2 Antibody, HRP conjugated	Human	ELISA
CSB-PA896902LC01HU	YTHDF2 Antibody, FITC conjugated	Human
CSB-PA896902LD01HU	YTHDF2 Antibody, Biotin conjugated	Human	ELISA

YTHDF2 Proteins

YTHDF2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP896902HU CSB-BP896902HU CSB-MP896902HU CSB-EP896902HU-B	Recombinant Human YTH domain family protein 2 (YTHDF2)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP896902HU	Recombinant Human YTH domain-containing family protein 2 (YTHDF2)	E.coli
CSB-EP896902HU2	Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial	E.coli
CSB-EP896902HUc7	Recombinant Human YTH domain-containing family protein 2 (YTHDF2)	E.coli
CSB-EP896902HU1	Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial	E.coli

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YTHDF2

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