ZNF318

ZNF318, Zinc finger protein 318, also known as Zinc finger protein 318/Endocrine regulatory protein, is a transcription factor containing multiple C2H2-type zinc finger structural domains, encoded by its own genes in human cells.The mechanism of action of ZNF318 is to regulate the expression of downstream genes through the binding of ZNF318 to specific sequences in DNA. ZNF318 regulates the expression of downstream genes through the binding of its zinc finger domains to specific sequences in DNA. It is involved in various signaling pathways, including but not limited to the NF-κB signaling pathway, and affects cell proliferation, differentiation, and immune response.

ZNF318 has a wide range of biological significance, and it plays an important regulatory role in the cell. For example, ZNF318 is involved in the regulation of liver and small intestine metabolism and proliferation, and maintains the balance of liver metabolic compartmentalization and hepatocyte proliferation through coordinated action with the WNT/β-Catenin signaling pathway . In addition, the abnormal function of ZNF318 is associated with the development of many diseases, including tumors, metabolic diseases, etc. Therefore, it is also a potential target in drug development.

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Recombinant Human Zinc finger protein 318 (ZNF318), partial