ADAM17 Research Reagents

Disintegrin and metalloproteinase domain-containing protein 17 is a protein in humans that is encoded by ADAM17 gene. Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.

The following ADAM17 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ADAM17 Antibodies

ADAM17 Antibodies for Homo sapiens (Human)

ADAM17 Proteins

ADAM17 Proteins for Sus scrofa (Pig)

ADAM17 Proteins for Homo sapiens (Human)

ADAM17 ELISA Kit

ADAM17 ELISA Kit for Homo sapiens (Human)

ADAM17 ELISA Kit for Mus musculus (Mouse)

Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
Join Us with

Subscribe newsletter

Leave a message

© 2007-2022 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1