ASIP

ASIP encodes agouti signaling protein, a paracrine signaling molecule that regulates melanin production by antagonizing melanocortin 1 receptor (MC1R) in melanocytes. It inhibits α-melanocyte-stimulating hormone (α-MSH)-induced eumelanin synthesis, promoting pheomelanin production instead.
ASIP is linked to pigmentation disorders like piebaldism and melanoma risk via MC1R signaling modulation. Emerging research explores its potential in metabolic syndrome through hypothalamic melanocortin 4 receptor (MC4R) interactions, though no targeted drugs are currently approved.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ASIP Antibody (CSB-PA002212LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA002212LA01HU at dilution of 1:100

Immunofluorescent analysis of MCF-7 cells using CSB-PA002212LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following ASIP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ASIP Antibodies

ASIP Proteins

ASIP Antibodies

ASIP Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA002212LA01HU	ASIP Antibody	Human	ELISA, IHC, IF
CSB-PA002212LB01HU	ASIP Antibody, HRP conjugated	Human	ELISA
CSB-PA002212LD01HU	ASIP Antibody, Biotin conjugated	Human	ELISA

ASIP Antibodies for Bos taurus (Bovine)

Code	Product Name	Species Reactivity	Application
CSB-PA639982ZA01BO	ASIP Antibody	Bos taurus	ELISA, WB (ensure identification of antigen)

ASIP Proteins

ASIP Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP002212MO CSB-EP002212MO CSB-BP002212MO CSB-MP002212MO CSB-EP002212MO-B	Recombinant Mouse Agouti-signaling protein (Asip)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP002212HU CSB-BP002212HU CSB-MP002212HU CSB-EP002212HU-B	Recombinant Human Agouti-signaling protein (ASIP)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP002212HU1	Recombinant Human Agouti-signaling protein (ASIP), partial	E.coli
CSB-EP002212HU	Recombinant Human Agouti-signaling protein (ASIP)	E.coli

ASIP Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP002212MOW CSB-EP002212MOW CSB-BP002212MOW CSB-MP002212MOW CSB-EP002212MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Vulpes vulpes (Red fox)

Code	Product Name	Source
CSB-YP002212VFW CSB-EP002212VFW CSB-BP002212VFW CSB-MP002212VFW CSB-EP002212VFW-B	Recombinant Vulpes vulpes Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca sylvanus (Barbary macaque)

Code	Product Name	Source
CSB-YP002212MNE CSB-EP002212MNE CSB-BP002212MNE CSB-MP002212MNE CSB-EP002212MNE-B	Recombinant Macaca sylvanus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca nigra (Celebes black macaque) (Crested black macaque)

Code	Product Name	Source
CSB-YP002212MNA CSB-EP002212MNA CSB-BP002212MNA CSB-MP002212MNA CSB-EP002212MNA-B	Recombinant Macaca nigra Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Trachypithecus auratus (Javan langur)

Code	Product Name	Source
CSB-YP002212TKK CSB-EP002212TKK CSB-BP002212TKK CSB-MP002212TKK CSB-EP002212TKK-B	Recombinant Trachypithecus auratus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP002212CYL CSB-EP002212CYL CSB-BP002212CYL CSB-MP002212CYL CSB-EP002212CYL-B	Recombinant Callithrix jacchus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Callimico goeldii (Goeldi's marmoset)

Code	Product Name	Source
CSB-YP002212CYI CSB-EP002212CYI CSB-BP002212CYI CSB-MP002212CYI CSB-EP002212CYI-B	Recombinant Callimico goeldii Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP002212ERI CSB-EP002212ERI CSB-BP002212ERI CSB-MP002212ERI CSB-EP002212ERI-B	Recombinant Papio anubis Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Callithrix pygmaea (Pygmy marmoset) (Cebuella pygmaea)

Code	Product Name	Source
CSB-YP002212DQT CSB-EP002212DQT CSB-BP002212DQT CSB-MP002212DQT CSB-EP002212DQT-B	Recombinant Cebuella pygmaea Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca nemestrina (Pig-tailed macaque)

Code	Product Name	Source
CSB-YP002212MOX CSB-EP002212MOX CSB-BP002212MOX CSB-MP002212MOX CSB-EP002212MOX-B	Recombinant Macaca nemestrina Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Callithrix geoffroyi (Geoffroy's marmoset)

Code	Product Name	Source
CSB-YP002212CYK CSB-EP002212CYK CSB-BP002212CYK CSB-MP002212CYK CSB-EP002212CYK-B	Recombinant Callithrix geoffroyi Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Leontopithecus chrysomelas (Golden-headed lion tamarin)

Code	Product Name	Source
CSB-YP002212LLN CSB-EP002212LLN CSB-BP002212LLN CSB-MP002212LLN CSB-EP002212LLN-B	Recombinant Leontopithecus chrysomelas Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Trachypithecus francoisi (Francois' leaf monkey) (Presbytis francoisi)

Code	Product Name	Source
CSB-YP002212TOZ CSB-EP002212TOZ CSB-BP002212TOZ CSB-MP002212TOZ CSB-EP002212TOZ-B	Recombinant Trachypithecus francoisi Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Leontopithecus rosalia (Golden lion tamarin)

Code	Product Name	Source
CSB-YP002212LLO CSB-EP002212LLO CSB-BP002212LLO CSB-MP002212LLO CSB-EP002212LLO-B	Recombinant Leontopithecus rosalia Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca nigrescens (Gorontalo macaque) (Macaca nigra nigrescens)

Code	Product Name	Source
CSB-YP002212MNB CSB-EP002212MNB CSB-BP002212MNB CSB-MP002212MNB CSB-EP002212MNB-B	Recombinant Macaca nigrescens Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca arctoides (Stump-tailed macaque)

Code	Product Name	Source
CSB-YP002212MOU CSB-EP002212MOU CSB-BP002212MOU CSB-MP002212MOU CSB-EP002212MOU-B	Recombinant Macaca arctoides Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca cyclopis (Taiwan macaque)

Code	Product Name	Source
CSB-YP002212MMW CSB-EP002212MMW CSB-BP002212MMW CSB-MP002212MMW CSB-EP002212MMW-B	Recombinant Macaca cyclopis Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca silenus (Lion-tailed macaque)

Code	Product Name	Source
CSB-YP002212MNC CSB-EP002212MNC CSB-BP002212MNC CSB-MP002212MNC CSB-EP002212MNC-B	Recombinant Macaca silenus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca hecki (Heck's macaque)

Code	Product Name	Source
CSB-YP002212MMY CSB-EP002212MMY CSB-BP002212MMY CSB-MP002212MMY CSB-EP002212MMY-B	Recombinant Macaca hecki Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca fuscata fuscata (Japanese macaque)

Code	Product Name	Source
CSB-YP002212MMX CSB-EP002212MMX CSB-BP002212MMX CSB-MP002212MMX CSB-EP002212MMX-B	Recombinant Macaca fuscata fuscata Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca assamensis (Assam macaque) (Assamese macaque)

Code	Product Name	Source
CSB-YP002212MMV CSB-EP002212MMV CSB-BP002212MMV CSB-MP002212MMV CSB-EP002212MMV-B	Recombinant Macaca assamensis Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca maura (Moor macaque)

Code	Product Name	Source
CSB-YP002212MMZ CSB-EP002212MMZ CSB-BP002212MMZ CSB-MP002212MMZ CSB-EP002212MMZ-B	Recombinant Macaca maura Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca sinica (Toque macaque) (Toque monkey)

Code	Product Name	Source
CSB-YP002212MND CSB-EP002212MND CSB-BP002212MND CSB-MP002212MND CSB-EP002212MND-B	Recombinant Macaca sinica Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Code	Product Name	Source
CSB-YP630272DSU CSB-EP630272DSU CSB-BP630272DSU CSB-MP630272DSU CSB-EP630272DSU-B	Recombinant Chlorocebus aethiops Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP631305GGZ CSB-EP631305GGZ CSB-BP631305GGZ CSB-MP631305GGZ CSB-EP631305GGZ-B	Recombinant Gorilla gorilla gorilla Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Colobus polykomos (Western black-and-white colobus monkey)

Code	Product Name	Source
CSB-YP632343DVI CSB-EP632343DVI CSB-BP632343DVI CSB-MP632343DVI CSB-EP632343DVI-B	Recombinant Colobus polykomos Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Pongo pygmaeus (Bornean orangutan)

Code	Product Name	Source
CSB-YP632344EXP CSB-EP632344EXP CSB-BP632344EXP CSB-MP632344EXP CSB-EP632344EXP-B	Recombinant Pongo pygmaeus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca radiata (Bonnet macaque)

Code	Product Name	Source
CSB-YP633596MOY CSB-EP633596MOY CSB-BP633596MOY CSB-MP633596MOY CSB-EP633596MOY-B	Recombinant Macaca radiata Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Erythrocebus patas (Red guenon) (Cercopithecus patas)

Code	Product Name	Source
CSB-YP635285EGU CSB-EP635285EGU CSB-BP635285EGU CSB-MP635285EGU CSB-EP635285EGU-B	Recombinant Erythrocebus patas Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Semnopithecus entellus (Hanuman langur) (Presbytis entellus)

Code	Product Name	Source
CSB-YP636312SEU CSB-EP636312SEU CSB-BP636312SEU CSB-MP636312SEU CSB-EP636312SEU-B	Recombinant Semnopithecus entellus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

Code	Product Name	Source
CSB-YP636313EQU CSB-EP636313EQU CSB-BP636313EQU CSB-MP636313EQU CSB-EP636313EQU-B	Recombinant Pan paniscus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Cercopithecus mitis (Blue monkey)

Code	Product Name	Source
CSB-YP637353CCAF CSB-EP637353CCAF CSB-BP637353CCAF CSB-MP637353CCAF CSB-EP637353CCAF-B	Recombinant Cercopithecus mitis Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP637354EQV CSB-EP637354EQV CSB-BP637354EQV CSB-MP637354EQV CSB-EP637354EQV-B	Recombinant Pan troglodytes Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)

Code	Product Name	Source
CSB-YP638527TOY CSB-EP638527TOY CSB-BP638527TOY CSB-MP638527TOY CSB-EP638527TOY-B	Recombinant Trachypithecus cristatus Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP638528MOV CSB-EP638528MOV CSB-BP638528MOV CSB-MP638528MOV CSB-EP638528MOV-B	Recombinant Macaca fascicularis Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP639982BO CSB-MP639982BO CSB-EP639982BO-B	Recombinant Bovine Agouti-signaling protein (ASIP)	Yeast Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP639982BO	Recombinant Bovine Agouti-signaling protein (ASIP)	E.coli
CSB-BP639982BO	Recombinant Bovine Agouti-signaling protein (ASIP)	Baculovirus

ASIP Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP736035DO CSB-EP736035DO CSB-BP736035DO CSB-MP736035DO CSB-EP736035DO-B	Recombinant Dog Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP758206PI CSB-EP758206PI CSB-BP758206PI CSB-MP758206PI CSB-EP758206PI-B	Recombinant Pig Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP772945CA CSB-EP772945CA CSB-BP772945CA CSB-MP772945CA CSB-EP772945CA-B	Recombinant Cat Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP850188HO CSB-EP850188HO CSB-BP850188HO CSB-MP850188HO CSB-EP850188HO-B	Recombinant Horse Agouti-signaling protein (ASIP)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ASIP Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP857472RA CSB-EP857472RA CSB-BP857472RA CSB-MP857472RA CSB-EP857472RA-B	Recombinant Rat Agouti-signaling protein (Asip)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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