Baculoviral IAP repeat-containing protein 6 is a protein in humans that is encoded by BIRC6 gene. Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
The following BIRC6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BIRC6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA920513 | BIRC6 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA671607 | BIRC6 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA279642 | BIRC6 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA271700 | BIRC6 Antibody |
Human,Mouse | ELISA,IHC |
BIRC6 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP002707MO CSB-EP002707MO CSB-BP002707MO CSB-MP002707MO CSB-EP002707MO-B |
Recombinant Mouse Baculoviral IAP repeat-containing protein 6 (Birc6), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BIRC6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP868294HU CSB-EP868294HU CSB-BP868294HU CSB-MP868294HU CSB-EP868294HU-B |
Recombinant Human Baculoviral IAP repeat-containing protein 6 (BIRC6), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |