As a neurotoxin, BTX protein has a unique dual-headed Kazal-type serine protease inhibitor structure, which can selectively act on peripheral cholinergic nerve terminals and inhibit the release of acetylcholine. It binds highly selectively to nerve terminals, enters target cells through receptor-mediated phagocytosis, and causes dysfunction of presynaptic terminals. Although the specific signaling pathways of BTX protein are not fully understood, it can be speculated that it may involve complex signaling transduction processes, including the activation of neurotransmitter receptors, the opening of ion channels, and the regulation of intracellular signaling molecules. In addition, different types of BTX proteins have differences in potency and intracellular targets, which further increases the complexity of their signaling pathways
The following BTX reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BTX Proteins for Blarina brevicauda (Northern short-tailed shrew)
Code | Product Name | Source |
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CSB-YP765725BTI CSB-EP765725BTI CSB-BP765725BTI CSB-MP765725BTI CSB-EP765725BTI-B |
Recombinant Blarina brevicauda Blarina toxin (BTX) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |