Caspase recruitment domain-containing protein 11 is a protein in humans that is encoded by CARD11 gene. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway.

CARD11 Antibodies

CARD11 Antibodies for Homo sapiens (Human)

CARD11 Proteins

CARD11 Proteins for Mus musculus (Mouse)

CARD11 Proteins for Homo sapiens (Human)


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