CD200 receptor 1 (CD200R1) is a type I membrane glycoprotein that belongs to the immunoglobulin superfamily (IgSF). Both receptors and ligands are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R1 is an inhibitory receptor expressed on T cells and myeloid cells, receptor-ligand interactions may play a role in myeloid down-regulation signaling, and CD200R1 can serve as an immune checkpoint target. In addition to their inhibitory effects on macrophages, CD200/CD200R also plays an important role in regulatory T cells, allergic responses, autoimmune diseases, allografts, neurological diseases and other autoimmune-related diseases. Multiple components of the CD200R1 pathway have been observed to be associated with tumor immunity, including the receptor, its cognate ligand CD200, and its downstream adaptor protein DOK2. Single-cell RNA sequencing of different types of tumors observed CD200R1 expression in tumor-infiltrating lymphocytes.
The following CD200R1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CD200R1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA851547ESR1HU | CD200R1 Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA851547ESR2HU | CD200R1 Antibody |
Human, Mouse | ELISA, WB |
CSB-PA003608 | CD200R1 Antibody |
Human | WB, ELISA |
CSB-PA564323 | CD200R1 Antibody |
Human | ELISA,IHC |
CSB-PA903031 | CD200R1 Antibody |
Human | ELISA,IHC |
CD200R1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP851547HU CSB-EP851547HU CSB-BP851547HU CSB-MP851547HU CSB-EP851547HU-B |
Recombinant Human Cell surface glycoprotein CD200 receptor 1 (CD200R1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD200R1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP863669MO CSB-EP863669MO CSB-BP863669MO CSB-MP863669MO CSB-EP863669MO-B |
Recombinant Mouse Cell surface glycoprotein CD200 receptor 1 (Cd200r1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD200R1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP866839RA CSB-EP866839RA CSB-BP866839RA CSB-MP866839RA CSB-EP866839RA-B |
Recombinant Rat Cell surface glycoprotein CD200 receptor 1 (Cd200r1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD200R1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF004896BO | Recombinant Bovine Cell surface glycoprotein CD200 receptor 1 (CD200R1) |
in vitro E.coli expression system |
CSB-YP004896BO1 CSB-EP004896BO1 CSB-BP004896BO1 CSB-MP004896BO1 CSB-EP004896BO1-B |
Recombinant Bovine Cell surface glycoprotein CD200 receptor 1 (CD200R1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |