CD47, also known as integrin associated protein (IAP) is a transmembrane protein encoded by the CD47 gene in human.It belongs to the immunoglobulin superfamily[5] and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). It has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Moreover, this protein plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). It can bind to SIRPA as a receptor to prevent maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
Most Popular Product:
Recombinant Human Leukocyte surface antigen CD47(CD47),partial (Active) (CSB-MP004940HU)
Validated Data
Greater than 93% as determined by SDS-PAGE.
Immobilized SIRPA (CSB-MP021334HU) at 2 μg/ml can bind human CD47, the EC50 of human CD47 protein is 65.91-82.42 ng/ml.
Human SIRPA protein His/Myc tag (CSB-MP021334HU) captured on COOH chip can bind Human CD47 protein Fc tag with an affinity constant of 19.1 nM as detected by LSPR Assay.
The following CD47 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CD47 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004940GA01HU | CD47 Antibody |
Human | ELISA,WB |
CSB-PA005993 | CD47 Antibody |
Human | WB, ELISA |
CSB-PA445679 | CD47 Antibody |
Human | ELISA,WB,IHC |
CSB-PA911004 | CD47 Antibody |
Human | ELISA,IHC |
CSB-PA004940LA01HU | CD47 Antibody |
Human | ELISA, IHC, IF |
CSB-PA004940LB01HU | CD47 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA004940LC01HU | CD47 Antibody, FITC conjugated |
Human | |
CSB-PA004940LD01HU | CD47 Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA802124A0HU | CD47 Antibody |
Human | ELISA, WB, IHC, IF |
CD47 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF713985MO | Recombinant Mouse Leukocyte surface antigen CD47(Cd47) |
in vitro E.coli expression system |
CSB-YP713985MO1 CSB-EP713985MO1 CSB-BP713985MO1 CSB-MP713985MO1 CSB-EP713985MO1-B |
Recombinant Mouse Leukocyte surface antigen CD47(Cd47),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP005351MO | Recombinant Mouse Leukocyte surface antigen CD47(Cd47),partial (Active) |
Mammalian cell |
CD47 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-CF872379PI | Recombinant Pig Leukocyte surface antigen CD47(CD47) |
in vitro E.coli expression system |
CSB-YP872379PI1 CSB-EP872379PI1 CSB-BP872379PI1 CSB-MP872379PI1 CSB-EP872379PI1-B |
Recombinant Pig Leukocyte surface antigen CD47(CD47),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD47 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF885628BO | Recombinant Bovine Leukocyte surface antigen CD47(CD47) |
in vitro E.coli expression system |
CSB-YP885628BO1 CSB-EP885628BO1 CSB-BP885628BO1 CSB-MP885628BO1 CSB-EP885628BO1-B |
Recombinant Bovine Leukocyte surface antigen CD47(CD47),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD47 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF004940RA | Recombinant Rat Leukocyte surface antigen CD47(Cd47) |
in vitro E.coli expression system |
CSB-YP004940RA1 CSB-EP004940RA1 CSB-BP004940RA1 CSB-MP004940RA1 CSB-EP004940RA1-B |
Recombinant Rat Leukocyte surface antigen CD47(Cd47),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD47 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-CF729089PYX | Recombinant Pongo abelii Leukocyte surface antigen CD47(CD47) |
in vitro E.coli expression system |
CSB-YP729089PYX1 CSB-EP729089PYX1 CSB-BP729089PYX1 CSB-MP729089PYX1 CSB-EP729089PYX1-B |
Recombinant Pongo abelii Leukocyte surface antigen CD47(CD47),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD47 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-AP005201HU | Recombinant Human Leukocyte surface antigen CD47(CD47),partial (Active) |
Mammalian cell |
CSB-AP005211HU | Recombinant Human Leukocyte surface antigen CD47(CD47),partial (Active) |
Mammalian cell |
CSB-MP004940HU | Recombinant Human Leukocyte surface antigen CD47(CD47),partial (Active) |
Mammalian cell |
CD47 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL004940HU | Human Leukocyte surface antigen CD47(CD47) ELISA kit |
serum, plasma, urine, tissue homogenates | 0.78 pg/mL |
CD47 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL004940MO | Mouse Leukocyte surface antigen CD47(CD47) ELISA kit |
serum, plasma,tissue homogenates | 3.9 pg/mL |