CDH6, also known as K-cadherin, is a crucial member of the type II cadherin family, characterized by its structure comprising an extracellular domain, a transmembrane region, and an intracellular tail. This unique architecture endows CDH6 with significant roles in cell adhesion and signal transduction. CDH6 is widely expressed in various tissues and organs, particularly at high levels in the kidney and gallbladder. Notably, overexpression of CDH6 has been observed in malignancies such as ovarian cancer and renal cell carcinoma, suggesting its close association with tumor development and progression. Although the specific signaling pathways of CDH6 remain incompletely understood, it is speculated that CDH6 may interact with other cell surface molecules or intracellular signaling molecules to regulate processes such as cell adhesion, migration, proliferation, and differentiation. Additionally, CDH6 plays a pivotal role in enterprise-level applications, where it integrates with Apache Hadoop ecosystem components like Ranger to provide comprehensive big data solutions that ensure data security and reliability. However, further research is needed to elucidate the precise signaling pathways and regulatory mechanisms of CDH6.
Recombinant Human Cadherin-6(CDH6),partial (Active)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 2μg/mL can bind Anti-CDH6 recombinant antibody (CSB-RA005055MA1HU),the EC50 is 2.421-2.802 ng/mL.
The following CDH6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CDH6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA005055ESR1HU | CDH6 Antibody |
Human | ELISA, WB, IHC |
CSB-PA004767 | CDH6 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA038132 | CDH6 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA789505 | CDH6 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-RA005055MA1HU | CDH6 Recombinant Monoclonal Antibody |
Human | ELISA |
CDH6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF005055HU | Recombinant Human Cadherin-6 (CDH6) |
in vitro E.coli expression system |
CSB-YP005055HU1 CSB-EP005055HU1 CSB-BP005055HU1 CSB-EP005055HU1-B |
Recombinant Human Cadherin-6 (CDH6), partial |
Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP005055HU1 | Recombinant Human Cadherin-6(CDH6),partial (Active) |
Mammalian cell |