CES1 encodes carboxylesterase 1, also commonly known as CES1A1. This enzyme hydrolyzes a wide range of endogenous and exogenous esters, playing crucial roles in lipid metabolism and drug detoxification. Mechanistically, it cleaves ester bonds in substrates. It is involved in the peroxisome proliferator - activated receptor (PPAR) signaling pathway.
Abnormal CES1 activity is associated with several diseases, including obesity and hyperlipidemia. In drug development, CES1 is a key target for drugs treating lipid - related disorders. Some inhibitors are under pre - clinical studies to modulate CES1 function for better therapeutic outcomes.
Recombinant Human Adenosine deaminase CECR1 (CECR1), partial (CSB-EP878938HU1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Adenosine deaminase CECR1(CECR1) ELISA kit (CSB-EL005187HU)
Validated Data
Code: CSB-EL005187HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.078 ng/mL
Detection Range: 0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following CES1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CES1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP878938HU CSB-EP878938HU CSB-BP878938HU CSB-MP878938HU CSB-EP878938HU-B |
Recombinant Human Adenosine deaminase CECR1 (CECR1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP878938HU1 | Recombinant Human Adenosine deaminase CECR1 (CECR1), partial | E.coli |
CES1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL005187HU | Human Adenosine deaminase CECR1(CECR1) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |