CHMP1A

Charged multivesicular body protein 1a is a protein in humans that is encoded by CHMP1A gene. Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).

CHMP1A Antibodies

CHMP1A Antibodies for Homo sapiens (Human)

CHMP1A Antibodies for Arabidopsis thaliana (Mouse-ear cress)

CHMP1A Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP1A Proteins

CHMP1A Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

CHMP1A Proteins for Xenopus laevis (African clawed frog)

CHMP1A Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP1A Proteins for Mus musculus (Mouse)

CHMP1A Proteins for Homo sapiens (Human)

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