CHMP2A

Charged multivesicular body protein 2a is a protein in humans that is encoded by CHMP2A gene. Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.

CHMP2A Antibodies

CHMP2A Antibodies for Homo sapiens (Human)

CHMP2A Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP2A Proteins

CHMP2A Proteins for Homo sapiens (Human)

CHMP2A Proteins for Gallus gallus (Chicken)

CHMP2A Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

CHMP2A Proteins for Xenopus laevis (African clawed frog)

CHMP2A Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP2A Proteins for Mus musculus (Mouse)

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