Charged multivesicular body protein 4b is a protein in humans that is encoded by CHMP4B gene. Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.
The following CHMP4B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CHMP4B Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA078194 | CHMP4B Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA174578 | CHMP4B Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA887976ESR1HU | CHMP4B Antibody |
Human | ELISA, IHC |
CHMP4B Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA770386XA01DIL | chmp4b Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
CHMP4B Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP716934CH CSB-EP716934CH CSB-BP716934CH CSB-MP716934CH CSB-EP716934CH-B |
Recombinant Chicken Charged multivesicular body protein 4b (CHMP4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4B Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP733400XBE CSB-EP733400XBE CSB-BP733400XBE CSB-MP733400XBE CSB-EP733400XBE-B |
Recombinant Xenopus laevis Charged multivesicular body protein 4b (chmp4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4B Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
---|---|---|
CSB-YP743419XBF CSB-EP743419XBF CSB-BP743419XBF CSB-MP743419XBF CSB-EP743419XBF-B |
Recombinant Xenopus tropicalis Charged multivesicular body protein 4b (chmp4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4B Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP770386DIL CSB-EP770386DIL CSB-BP770386DIL CSB-MP770386DIL CSB-EP770386DIL-B |
Recombinant Danio rerio Charged multivesicular body protein 4b (chmp4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4B Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP872009MO CSB-EP872009MO CSB-BP872009MO CSB-MP872009MO CSB-EP872009MO-B |
Recombinant Mouse Charged multivesicular body protein 4b (Chmp4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4B Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP887976HU CSB-BP887976HU CSB-MP887976HU CSB-EP887976HU-B |
Recombinant Human Charged multivesicular body protein 4b (CHMP4B) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP887976HU | Recombinant Human Charged multivesicular body protein 4b (CHMP4B) |
E.coli |