CLEC12A is a crucial cell surface receptor belonging to the C-type lectin/C-type lectin-like domain superfamily. Possessing specific structural characteristics, it effectively binds and interacts with other molecules. Functionally, CLEC12A is involved in various biological processes such as cell adhesion, signal transduction, glycoprotein turnover, and immune and inflammatory responses. It also serves as a negative regulator of granulocyte and monocyte function, participating in the balanced regulation of the immune system. In terms of signaling pathways, CLEC12A can promote the activity of target MAP kinase proteases, triggering intracellular signaling transduction events that affect cell proliferation, differentiation, and apoptosis. Furthermore, it is closely related to other CTL/CTLD superfamily members, potentially collaborating in complex biological processes and signaling networks. However, the specific mechanism of CLEC12A in signaling pathways remains to be further investigated. Such studies will contribute to a more comprehensive understanding of CLEC12A's role in physiological and pathological processes, providing new ideas and methods for the treatment of related diseases.
Recombinant Human C-type lectin domain family 12 member A (CLEC12A), partial
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following CLEC12A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CLEC12A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA725176ESR1HU | CLEC12A Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA725176ESR2HU | CLEC12A Antibody |
Human, Mouse | ELISA, WB, IF |
CLEC12A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP725176HU CSB-EP725176HU CSB-BP725176HU CSB-MP725176HU CSB-EP725176HU-B |
Recombinant Human C-type lectin domain family 12 member A (CLEC12A), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |