Cyclic nucleotide-gated cation channel alpha-3 is a protein in humans that is encoded by CNGA3 gene. Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
The following CNGA3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CNGA3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA005644GA01HU | CNGA3 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA292433 | CNGA3 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA185605 | CNGA3 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA613670DSR1HU | CNGA3 Antibody |
Human | ELISA, IHC |
CNGA3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF888333MO | Recombinant Mouse Cyclic nucleotide-gated cation channel alpha-3 (Cnga3) |
in vitro E.coli expression system |
CSB-YP888333MO1 CSB-EP888333MO1 CSB-BP888333MO1 CSB-MP888333MO1 CSB-EP888333MO1-B |
Recombinant Mouse Cyclic nucleotide-gated cation channel alpha-3 (Cnga3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CNGA3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF613670HU | Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 (CNGA3) |
in vitro E.coli expression system |
CSB-YP613670HU1 CSB-EP613670HU1 CSB-BP613670HU1 CSB-MP613670HU1 CSB-EP613670HU1-B |
Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 (CNGA3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CNGA3 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF643680BO | Recombinant Bovine Cyclic nucleotide-gated cation channel alpha-3 (CNGA3) |
in vitro E.coli expression system |
CSB-YP643680BO1 CSB-EP643680BO1 CSB-BP643680BO1 CSB-MP643680BO1 CSB-EP643680BO1-B |
Recombinant Bovine Cyclic nucleotide-gated cation channel alpha-3 (CNGA3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |