CREB-regulated transcription coactivator 2 is a protein in humans that is encoded by CRTC2 gene. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
The following CRTC2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CRTC2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006001GA01HU | CRTC2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA832743 | CRTC2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA706631LA01HU | CRTC2 Antibody |
Human | ELISA, IHC, IF |
CRTC2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP663643MO CSB-EP663643MO CSB-BP663643MO CSB-MP663643MO CSB-EP663643MO-B |
Recombinant Mouse CREB-regulated transcription coactivator 2 (Crtc2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CRTC2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP667310RA CSB-EP667310RA CSB-BP667310RA CSB-MP667310RA CSB-EP667310RA-B |
Recombinant Rat CREB-regulated transcription coactivator 2 (Crtc2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CRTC2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP706631HU CSB-EP706631HU CSB-BP706631HU CSB-MP706631HU CSB-EP706631HU-B |
Recombinant Human CREB-regulated transcription coactivator 2 (CRTC2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |