CTSZ

CTSZ, also known as Cathepsin Z, is a lysosomal cysteine protease. It is also commonly referred to as Cathepsin X or Cathepsin P. This enzyme plays a key role in the degradation of proteins within lysosomes and participates in extracellular matrix remodeling. It is involved in the MAPK and PI3K - AKT signaling pathways.
CTSZ has been associated with various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. In the field of drug development, efforts are underway to design specific inhibitors of CTSZ to target these diseases. These potential drugs aim to regulate the protease's activity and thus alleviate associated pathological conditions.