CYSLTR2

The CYSLTR2 gene encodes the protein Cysteinyl Leukotriene Receptor 2 (CLTR2), also known as CysLT2. This receptor plays a crucial role in mediating the effects of leukotrienes, particularly in the context of inflammatory responses. It is involved in various signaling pathways, including those regulating acute and chronic itching. CYSLTR2 is associated with diseases such as asthma and atopic dermatitis, where its dysregulation can exacerbate symptoms. Research into CYSLTR2 has led to the development of potential therapeutic agents targeting this receptor for the treatment of these conditions.