DHPS dihydrofolate synthase is a key enzyme responsible for catalyzing specific reactions in the biosynthesis of tetrahydrofolic acid. As a carrier of one-carbon units, tetrahydrofolic acid plays a crucial role in cellular metabolism, participating in the synthesis of important substances such as purines and thymine. DHPS converts substrates into dihydrofolate through its specific catalytic active site, which is a key step in the synthesis pathway of tetrahydrofolic acid. Functionally, DHPS is crucial for maintaining the homeostasis of tetrahydrofolic acid in cells, which in turn affects biological processes such as cell proliferation, differentiation, and apoptosis. Although DHPS itself does not directly participate in signal transduction, the synthesis and metabolism of tetrahydrofolic acid indirectly affect the regulation of intracellular signaling pathways. Therefore, DHPS may indirectly participate in the regulation of intracellular signaling pathways by regulating the synthesis of tetrahydrofolic acid.
Validated Data
Western Blot analysis of K562 cells using DHS Polyclonal Antibody
Western Blot analysis of K562 cells using DHS Polyclonal Antibody
The following DHPS reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DHPS Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA002145 | DHPS Antibody |
Human | WB, ELISA |
CSB-PA006854LA01HU | DHPS Antibody |
Human | ELISA, IHC |
DHPS Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP006854HU CSB-EP006854HU CSB-BP006854HU CSB-MP006854HU CSB-EP006854HU-B |
Recombinant Human Deoxyhypusine synthase (DHPS) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |