Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.
The following DICER1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DICER1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006893GA01HU | DICER1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA556009 | DICER1 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA447308 | DICER1 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA891575LA01HU | DICER1 Antibody |
Human | ELISA, IHC |
CSB-PA891575LB01HU | DICER1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA891575LC01HU | DICER1 Antibody, FITC conjugated |
Human |
DICER1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA747602XA01DIL | dicer1 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
DICER1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Code | Product Name | Source |
---|---|---|
CSB-YP006893DXU CSB-EP006893DXU CSB-BP006893DXU CSB-MP006893DXU CSB-EP006893DXU-B |
Recombinant Cricetulus griseus Endoribonuclease Dicer (DICER1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
---|---|---|
CSB-YP006893XBF CSB-EP006893XBF CSB-BP006893XBF CSB-MP006893XBF CSB-EP006893XBF-B |
Recombinant Xenopus tropicalis Endoribonuclease Dicer (dicer1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP638865CH CSB-EP638865CH CSB-BP638865CH CSB-MP638865CH CSB-EP638865CH-B |
Recombinant Chicken Endoribonuclease Dicer (DICER1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP744234BO CSB-EP744234BO CSB-BP744234BO CSB-MP744234BO CSB-EP744234BO-B |
Recombinant Bovine Endoribonuclease Dicer (DICER1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP747602DIL CSB-EP747602DIL CSB-BP747602DIL CSB-MP747602DIL CSB-EP747602DIL-B |
Recombinant Danio rerio Endoribonuclease Dicer (dicer1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP844456MO CSB-EP844456MO CSB-BP844456MO CSB-MP844456MO CSB-EP844456MO-B |
Recombinant Mouse Endoribonuclease Dicer (Dicer1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DICER1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP891575HU CSB-EP891575HU CSB-BP891575HU CSB-MP891575HU CSB-EP891575HU-B |
Recombinant Human Endoribonuclease Dicer (DICER1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |