DLX5

Homeobox protein DLX-5is a protein in humans that is encoded by DLX5 gene. Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

DLX5 Antibodies

DLX5 Antibodies for Homo sapiens (Human)

DLX5 Proteins

DLX5 Proteins for Mus musculus (Mouse)

DLX5 Proteins for Rattus norvegicus (Rat)

DLX5 Proteins for Gallus gallus (Chicken)

DLX5 Proteins for Homo sapiens (Human)

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