DYSF, also known as dystrophin, is a key cytoskeletal protein that plays a vital role in muscle cells. Its complex structure enables DYSF to interact with other proteins and molecules within the cell to form a stable cytoskeletal structure, providing mechanical support and maintaining the integrity of the muscle cell membrane. At the same time, DYSF also participates in intracellular signaling processes, regulating muscle contraction and relaxation, ensuring normal muscle function. However, when DYSF mutates or expresses abnormally, it may lead to genetic diseases such as muscular dystrophy, seriously affecting the quality of life of patients. In the signaling pathway, DYSF interacts with various proteins and molecules to jointly regulate the physiological activities of muscle cells.
Validated Data
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA007314LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007314LA01HU at dilution of 1:100
Immunofluorescence staining of Hela cells with CSB-PA007314LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
The following DYSF reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DYSF Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA184651 | DYSF Antibody |
Human,Mouse | ELISA,WB |
CSB-PA060232 | DYSF Antibody |
Human,Mouse | WB, IF, ELISA |
CSB-PA007314LA01HU | DYSF Antibody |
Human | ELISA, IHC, IF |
CSB-PA007314LB01HU | DYSF Antibody, HRP conjugated |
Human | ELISA |
CSB-PA007314LC01HU | DYSF Antibody, FITC conjugated |
Human |
DYSF Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP007314HU CSB-EP007314HU CSB-BP007314HU CSB-MP007314HU CSB-EP007314HU-B |
Recombinant Human Dysferlin (DYSF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |