Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.
The following EPHA7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
EPHA7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007727GA01HU | EPHA7 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA202937 | Phospho-EPHA7 (Tyr791) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA284968 | EPHA7 (Ab-791) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA235595 | EPHA7 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA008063 | Phospho-EPHA7 (Y791) Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA008064 | EPHA7 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA008065 | EPHA7 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA047259 | EPHA7 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA618004LA01HU | EPHA7 Antibody |
Human | ELISA, IHC, IF |
CSB-PA618004LB01HU | EPHA7 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA618004LC01HU | EPHA7 Antibody, FITC conjugated |
Human | |
CSB-PA618004LD01HU | EPHA7 Antibody, Biotin conjugated |
Human | ELISA |
EPHA7 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP007727RA CSB-EP007727RA CSB-BP007727RA CSB-MP007727RA CSB-EP007727RA-B |
Recombinant Rat Ephrin type-A receptor 7 (Epha7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EPHA7 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP007727CH CSB-EP007727CH CSB-BP007727CH CSB-MP007727CH CSB-EP007727CH-B |
Recombinant Chicken Ephrin type-A receptor 7 (EPHA7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EPHA7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618004HU CSB-EP618004HU CSB-BP618004HU CSB-MP618004HU CSB-EP618004HU-B |
Recombinant Human Ephrin type-A receptor 7 (EPHA7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EPHA7 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP733797MO CSB-EP733797MO CSB-BP733797MO CSB-MP733797MO CSB-EP733797MO-B |
Recombinant Mouse Ephrin type-A receptor 7 (Epha7), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |