FBXW11

F-box/WD repeat-containing protein 11 is a protein in humans that is encoded by FBXW11 gene. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. SCF(FBXW11) mediates the ubiquitination of CEP68.

The following FBXW11 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FBXW11 Antibodies

FBXW11 Proteins

FBXW11 Antibodies

FBXW11 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA008521GA01HU	FBXW11 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA891721ESR2HU	FBXW11 Antibody	Human	ELISA, IHC

FBXW11 Proteins

FBXW11 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP722546MO CSB-EP722546MO CSB-BP722546MO CSB-MP722546MO CSB-EP722546MO-B	Recombinant Mouse F-box/WD repeat-containing protein 11 (Fbxw11)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FBXW11 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP891721HU CSB-BP891721HU CSB-MP891721HU CSB-EP891721HU-B	Recombinant Human F-box/WD repeat-containing protein 11 (FBXW11)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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