The FMR1 gene encodes the Fragile X Mental Retardation Protein (FMRP), which structurally binds RNA and associates with multiprotein complexes. Functionally, FMRP regulates post-transcriptional gene expression, facilitating mRNA transport, translation, and localization. It plays a crucial role in synaptic function, neuronal development, and learning and memory processes. While the direct signaling pathways involving FMR1 are not fully understood, FMRP likely functions within a complex network of intracellular interactions related to neuronal activity and cellular growth. Mutations in FMR1, such as the expansion of the CGG trinucleotide repeat, can lead to Fragile X Syndrome, disrupting FMRP function and cellular processes. Therefore, FMR1 is a crucial gene in maintaining normal cellular function and preventing neurological disorders.
Human Fragile X mental retardation 1 protein(FMR1) ELISA kit
Validated Data
Code:CSB-EL008756HU
Size:96T/48T
Sensitivity:3.9 pg/mL
Detection Range:15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following FMR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FMR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008756GA01HU | FMR1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA952632 | FMR1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA916967 | FMR1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
FMR1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL008756HU | Human Fragile X mental retardation 1 protein(FMR1) ELISA kit |
serum, plasma, tissue homogenates | 3.9 pg/mL |