FOXQ1 encodes the forkhead box Q1 protein, a member of the FOX transcription factor family. It lacks widely recognized aliases but is critical for regulating epithelial-mesenchymal transition (EMT) by activating genes like E-cadherin repressors.
FOXQ1 modulates Wnt/β-catenin and TGF-β signaling pathways, promoting cancer cell proliferation and metastasis. Its overexpression correlates with colorectal, breast, and gastric cancers. No specific drugs targeting FOXQ1 are approved, though preclinical studies explore inhibitory small molecules to disrupt its transcriptional activity in oncology.
FOXQ1 Antibody (CSB-PA874860LA01HU)
Validated Data
Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: FOXQ1 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42 kDa
Observed band size: 42 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA874860LA01HU at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using CSB-PA874860LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following FOXQ1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FOXQ1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA874860LA01HU | FOXQ1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA874860LB01HU | FOXQ1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA874860LC01HU | FOXQ1 Antibody, FITC conjugated | Human |
FOXQ1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP874860HU CSB-EP874860HU CSB-BP874860HU CSB-MP874860HU CSB-EP874860HU-B |
Recombinant Human Forkhead box protein Q1 (FOXQ1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |