FZD2

FZD2, also known as Frizzled-2, is a protein with multiple aliases such as Fz-2. It plays a crucial role in the Wnt signaling pathway. FZD2 functions as a receptor for Wnt proteins, and upon ligand binding, it activates downstream signaling cascades that regulate cell proliferation, differentiation, and embryonic development.
Dysregulation of FZD2 is associated with various diseases, including certain cancers and developmental disorders. In the field of drug development, researchers are exploring potential inhibitors or modulators of FZD2 to target the aberrant Wnt signaling in disease conditions. Currently, some pre - clinical studies are underway to evaluate the effectiveness and safety of these agents.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FZD2 Antibody (CSB-PA596830)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using CSB-PA596830(FZD2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)

The following FZD2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FZD2 Antibodies

FZD2 Proteins

FZD2 Antibodies

FZD2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA008522	FZD2 Antibody	Human,Mouse,Rat	WB, IF, ELISA
CSB-PA596830	FZD2 Antibody	Human,Mouse,Rat	ELISA,IHC

FZD2 Proteins

FZD2 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-CF884854CH	Recombinant Chicken Frizzled-2 (FZD2)	in vitro E.coli expression system
CSB-YP884854CH1 CSB-EP884854CH1 CSB-BP884854CH1 CSB-MP884854CH1 CSB-EP884854CH1-B	Recombinant Chicken Frizzled-2 (FZD2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FZD2 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-CF886106XBE	Recombinant Xenopus laevis Frizzled-2 (fzd2)	in vitro E.coli expression system
CSB-YP886106XBE1 CSB-EP886106XBE1 CSB-BP886106XBE1 CSB-MP886106XBE1 CSB-EP886106XBE1-B	Recombinant Xenopus laevis Frizzled-2 (fzd2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FZD2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF622766HU	Recombinant Human Frizzled-2 (FZD2)	in vitro E.coli expression system
CSB-YP622766HU1 CSB-EP622766HU1 CSB-BP622766HU1 CSB-MP622766HU1 CSB-EP622766HU1-B	Recombinant Human Frizzled-2 (FZD2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP622766HU2	Recombinant Human Frizzled-2 (FZD2), partial	Mammalian cell
CSB-MP622766HU	Recombinant Human Frizzled-2 (FZD2)-VLPs	Mammalian cell

FZD2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF881309MO	Recombinant Mouse Frizzled-2 (Fzd2)	in vitro E.coli expression system
CSB-YP881309MO1 CSB-EP881309MO1 CSB-BP881309MO1 CSB-MP881309MO1 CSB-EP881309MO1-B	Recombinant Mouse Frizzled-2 (Fzd2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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FZD2

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