GPR55, G protein-coupled receptor 55, also known as LPI1, GPR55, PSIGPR53, is encoded by the human GPR55 gene, which is located on chromosome 2 in the q37.1 region.
GPR55 is a G protein-coupled receptor that may be involved in a variety of physiological and pathological processes through the activation of multiple signal transduction pathways. The ligands it activates include phytocannabinoids, endogenous cannabinoids, and lysophosphatidylinositol (LPI).
GPR55 has been associated with physiological functions such as mood, locomotion, cognition, learning, and memory, as well as with cannabinoid action and substance abuse. GPR55 may also be a new potential drug target for the treatment of inflammation, pain, diabetes, Parkinson's disease, neuropathic pain, and cancer. Studies have shown that GPR55 plays a role in modulating anxiety-like behavior, hippocampal neurogenesis, and neuroprotection.
GPR55 Antibody (CSB-PA009820OA01HU)
Validated Data
IHC image of CSB-PA009820OA01HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
The following GPR55 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GPR55 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009820OA01HU | GPR55 Antibody | Human | ELISA, IHC |
CSB-PA009820OB01HU | GPR55 Antibody, HRP conjugated | Human | ELISA |
CSB-PA009820OC01HU | GPR55 Antibody, FITC conjugated | Human | |
CSB-PA009820OD01HU | GPR55 Antibody, Biotin conjugated | Human | ELISA |
GPR55 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF661042MO | Recombinant Mouse G-protein coupled receptor 55 (Gpr55) | in vitro E.coli expression system |
CSB-YP661042MO1 CSB-EP661042MO1 CSB-BP661042MO1 CSB-MP661042MO1 CSB-EP661042MO1-B |
Recombinant Mouse G-protein coupled receptor 55 (Gpr55), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |