General transcription factor II-I is a protein in humans that is encoded by GTF2I gene. Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
The following GTF2I reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GTF2I Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010015GA01HU | GTF2I Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA009044 | Phospho-GTF2I (Y248) Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA253259 | GTF2I Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA291895 | GTF2I Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
GTF2I Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010015HU CSB-EP010015HU CSB-BP010015HU CSB-MP010015HU CSB-EP010015HU-B |
Recombinant Human General transcription factor II-I (GTF2I), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GTF2I Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP010015BO CSB-EP010015BO CSB-BP010015BO CSB-MP010015BO CSB-EP010015BO-B |
Recombinant Bovine General transcription factor II-I (GTF2I), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GTF2I Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP719446RA CSB-EP719446RA CSB-BP719446RA CSB-MP719446RA CSB-EP719446RA-B |
Recombinant Rat General transcription factor II-I (Gtf2i), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GTF2I Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP875371MO CSB-EP875371MO CSB-BP875371MO CSB-MP875371MO CSB-EP875371MO-B |
Recombinant Mouse General transcription factor II-I (Gtf2i), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |