Core histone macro-H2A.2 is a protein in humans that is encoded by H2AFY2 gene. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
The following H2AFY2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
H2AFY2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010099GA01HU | H2AFY2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA885785LA01HU | H2AFY2 Antibody |
Human | ELISA |
H2AFY2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP806045MO CSB-EP806045MO CSB-BP806045MO CSB-MP806045MO CSB-EP806045MO-B |
Recombinant Mouse Core histone macro-H2A.2 (H2afy2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
H2AFY2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP885785HU CSB-EP885785HU CSB-BP885785HU CSB-MP885785HU CSB-EP885785HU-B |
Recombinant Human Core histone macro-H2A.2 (H2AFY2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |