E3 ubiquitin-protein ligase HERC2 is a protein in humans that is encoded by HERC2 gene. E3 ubiquitin-protein ligase that regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in response to ionizing radiation (IR) and facilitates the assembly of UBE2N and RNF8 promoting DNA damage-induced formation of 'Lys-63'-linked ubiquitin chains. Acts as a mediator of binding specificity between UBE2N and RNF8. Involved in the maintenance of RNF168 levels. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of XPA which influences the circadian oscillation of DNA excision repair activity.
The following HERC2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HERC2 Antibodies for Drosophila melanogaster (Fruit fly)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA894265XA01DLU | HERC2 Antibody |
Drosophila melanogaster (Fruit fly) | ELISA, WB (ensure identification of antigen) |
HERC2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010293HU CSB-EP010293HU CSB-BP010293HU CSB-MP010293HU CSB-EP010293HU-B |
Recombinant Human E3 ubiquitin-protein ligase HERC2 (HERC2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HERC2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP703159MO CSB-EP703159MO CSB-BP703159MO CSB-MP703159MO CSB-EP703159MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase HERC2 (Herc2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HERC2 Proteins for Drosophila melanogaster (Fruit fly)
Code | Product Name | Source |
---|---|---|
CSB-YP894265DLU CSB-EP894265DLU CSB-BP894265DLU CSB-MP894265DLU CSB-EP894265DLU-B |
Recombinant Drosophila melanogaster Probable E3 ubiquitin-protein ligase HERC2 (HERC2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |