The protein corresponding to the gene HINT1 is histidine triad nucleotide-binding protein 1. Commonly known as HINT, this protein plays a critical role in regulating signal transduction pathways. It functions as a tumor suppressor by influencing cell - cycle progression and apoptosis. It is involved in multiple signaling cascades, such as the MAPK pathway.
In terms of diseases, HINT1 is associated with certain types of cancers and neurological disorders. Regarding drug development, research is underway to design small - molecule drugs that can modulate its activity, aiming to improve treatment outcomes for related diseases. However, more pre - clinical and clinical studies are needed to fully evaluate their efficacy and safety.
HINT1 Antibody (CSB-PA05639A0Rb)
Validated Data
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA05639A0Rb at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA05639A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following HINT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HINT1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA546607 | HINT1 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA570363 | HINT1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA038349 | HINT1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA925533 | HINT1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA05639A0Rb | HINT1 Antibody | Human | ELISA, IHC, IF |
CSB-PA05639B0Rb | HINT1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA05639C0Rb | HINT1 Antibody, FITC conjugated | Human | |
CSB-PA05639D0Rb | HINT1 Antibody, Biotin conjugated | Human | ELISA |
HINT1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP343812HU CSB-EP343812HU CSB-BP343812HU CSB-MP343812HU CSB-EP343812HU-B |
Recombinant Human Histidine triad nucleotide-binding protein 1 (HINT1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |