HLA-DRA

HLA-DRA encodes the HLA class II histocompatibility antigen DR alpha chain, a core subunit of MHC class II complexes. It heterodimerizes with DR beta chains (e.g., DRB1) to form functional antigen-presenting molecules, which bind exogenous peptides and present them to CD4+ T lymphocytes, triggering adaptive immune responses against pathogens.
Genetic variants of HLA-DRA are associated with autoimmune disorders like rheumatoid arthritis and systemic lupus erythematosus, as altered antigen presentation may drive self-reactivity. While direct drugs targeting HLA-DRA are limited, therapies modulating MHC class II-mediated T cell activation (e.g., co-stimulatory blockers) are used or in development, capitalizing on its role in immune regulation for disease management.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HLA-DRA Recombinant Monoclonal Antibody (CSB-RA188867A0HU)

Validated Data

Western Blot
Positive WB detected in: Raji whole cell lysate(30µg)
All lanes: HLA DRA antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 29 kDa
Observed band size: 35 kDa
Exposure time：2min40s

Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) ELISA kit (CSB-EL010497HU)

Validated Data

Code: CSB-EL010497HU

Size: 96T,5×96T,10×96T

Sensitivity: 4.68 pg/mL

Detection Range: 18.75 pg/mL-1200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following HLA-DRA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HLA-DRA Antibodies

HLA-DRA Proteins

HLA-DRA ELISA Kits

HLA-DRA Antibodies

HLA-DRA Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA17939C0Rb	HLA-DRA Antibody, FITC conjugated	Human
CSB-PA17939A0Rb	HLA-DRA Antibody	Human	ELISA, IHC
CSB-PA17939B0Rb	HLA-DRA Antibody, HRP conjugated	Human	ELISA
CSB-RA188867A0HU	HLA-DRA Recombinant Monoclonal Antibody	Human	ELISA, WB

HLA-DRA Proteins

HLA-DRA Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP360793HU	Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA)	Yeast
CSB-EP360793HU	Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA)	E.coli
CSB-BP360793HU CSB-MP360793HU CSB-EP360793HU-B	Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP360793HU1	Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA), partial	E.coli

HLA-DRA ELISA Kit

HLA-DRA ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL010497HU	Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) ELISA kit	serum, plasma, tissue homogenates	4.68 pg/mL

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HLA-DRA

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