Heat shock 70 kDa protein 6 is a protein in humans that is encoded by HSPA6 gene. Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins.
The following HSPA6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HSPA6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA863082HA01HU | HSPA6 Antibody |
Human | ELISA, WB |
HSPA6 Proteins for Saguinus oedipus (Cotton-top tamarin)
Code | Product Name | Source |
---|---|---|
CSB-YP863082SWB CSB-EP863082SWB CSB-BP863082SWB CSB-MP863082SWB CSB-EP863082SWB-B |
Recombinant Saguinus oedipus Heat shock 70 kDa protein 6 (HSPA6), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HSPA6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP863082HU | Recombinant Human Heat shock 70 kDa protein 6 (HSPA6), partial |
E.coli |
CSB-YP863082HU CSB-BP863082HU CSB-MP863082HU CSB-EP863082HU-B |
Recombinant human Heat shock 70 kDa protein 6 |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |