HSPH1

HSPH1, or heat shock protein family H (Hsp110) member 1, aliases include HSP105, HSP105A, HSP105B, NY-CO-25.HSPH1 is encoded by the human HSPH1 gene, which is located on chromosome 13 in the q12.3 region.
HSPH1 acts as a nucleotide exchange factor for the molecular chaperone heat shock homolog 71 kDa protein (Hsc70) and promotes the ATPase activity of Hsc70, which aids in the correct folding of proteins. HSPH1 acts as a holdase and inhibits the aggregation of misfolded proteins, including cystic fibrosis transmembrane conductance regulator (CFTR) proteins. HSPH1 has a role in maintaining protein homeostasis, response to cellular stress, and tumorigenesis, and its expression is elevated in several human cancers.

Popular Product:

HSPH1 Antibody (CSB-PA852885ESR1HU)

Validated Data

Western blot
All lanes: Heat shock protein 105 kDa
antibody at 1μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 97, 93, 98 kDa
Observed band size: 97 kDa

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA852885ESR1HU at dilution of 1:100

The following HSPH1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HSPH1 Antibodies

HSPH1 Proteins

HSPH1 Antibodies

HSPH1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA010869GA01HU	HSPH1 Antibody	Human,Mouse,Rat	ELISA,WB,IF
CSB-PA852885ESR1HU	HSPH1 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA852885ESR2HU	HSPH1 Antibody	Human	ELISA, IHC
CSB-PA002984	HSPH1 Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA183277	HSPH1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA684403	HSPH1 Antibody	Human,Mouse,Rat	ELISA,WB

HSPH1 Proteins

HSPH1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP609414BO CSB-EP609414BO CSB-BP609414BO CSB-MP609414BO CSB-EP609414BO-B	Recombinant Bovine Heat shock protein 105 kDa (HSPH1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSPH1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP713984MO CSB-EP713984MO CSB-BP713984MO CSB-MP713984MO CSB-EP713984MO-B	Recombinant Mouse Heat shock protein 105 kDa (Hsph1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSPH1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-YP717095DXU CSB-EP717095DXU CSB-BP717095DXU CSB-MP717095DXU CSB-EP717095DXU-B	Recombinant Cricetulus griseus Heat shock protein 105 kDa (HSPH1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSPH1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP724118RA CSB-EP724118RA CSB-BP724118RA CSB-MP724118RA CSB-EP724118RA-B	Recombinant Rat Heat shock protein 105 kDa (Hsph1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSPH1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP725283PYX CSB-EP725283PYX CSB-BP725283PYX CSB-MP725283PYX CSB-EP725283PYX-B	Recombinant Pongo abelii Heat shock protein 105 kDa (HSPH1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSPH1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP852885HU CSB-EP852885HU CSB-BP852885HU CSB-MP852885HU CSB-EP852885HU-B	Recombinant Human Heat shock protein 105 kDa (HSPH1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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