IDH1

Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate and CO₂. This is a two-step process, which involves oxidation of isocitrate to oxalosuccinate, followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD⁺ to NADH in the mitochondria. The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP⁺ as a cofactor instead of NAD⁺. They localize to the cytosol as well as the mitochondrion and peroxisome.

The following IDH1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

IDH1 Antibodies

IDH1 Proteins

IDH1 Antibodies

IDH1 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA010989LA01MO	Idh1 Antibody	Mouse	ELISA, IHC, IF

IDH1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA010989GA01HU	IDH1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA010989ESR1HU	IDH1 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA005688	IDH1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA964946	IDH1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA826954	IDH1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA010989EA01HU	IDH1 Antibody	Human, Mouse, Rat	ELISA, WB, IHC, IF
CSB-PA010989EB01HU	IDH1 Antibody, HRP conjugated	Human	ELISA
CSB-PA010989EC01HU	IDH1 Antibody, FITC conjugated	Human
CSB-PA010989ED01HU	IDH1 Antibody, Biotin conjugated	Human	ELISA

IDH1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA850685XA01DOA	IDH1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

IDH1 Antibodies for Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)

Code	Product Name	Species Reactivity	Application
CSB-PA517526XA01AZC	IDH1 Antibody	Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)	ELISA, WB (ensure identification of antigen)

IDH1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA341012XA01SVG	IDH1 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

IDH1 Antibodies for Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)

Code	Product Name	Species Reactivity	Application
CSB-PA526076XA01KBK	IDH1 Antibody	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	ELISA, WB (ensure identification of antigen)

IDH1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA521025XA01SXV	idh1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

IDH1 Proteins

IDH1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP010989PI CSB-EP010989PI CSB-BP010989PI CSB-MP010989PI CSB-EP010989PI-B	Recombinant Pig Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP010989RA CSB-EP010989RA CSB-BP010989RA CSB-MP010989RA CSB-EP010989RA-B	Recombinant Rat Isocitrate dehydrogenase [NADP] cytoplasmic (Idh1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP010989MO CSB-BP010989MO CSB-MP010989MO CSB-EP010989MO-B	Recombinant Mouse Isocitrate dehydrogenase [NADP] cytoplasmic (Idh1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP010989MO	Recombinant Mouse Isocitrate dehydrogenase [NADP] Cytoplasmic domain (Idh1), partial	E.coli

IDH1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP010989HU CSB-EP010989HU CSB-BP010989HU CSB-MP010989HU CSB-EP010989HU-B	Recombinant Human Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP010989HU(A4)	Recombinant Human Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	E.coli

IDH1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP341012SVG CSB-EP341012SVG CSB-BP341012SVG CSB-MP341012SVG CSB-EP341012SVG-B	Recombinant Saccharomyces cerevisiae Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)

Code	Product Name	Source
CSB-YP517526AZC CSB-EP517526AZC CSB-BP517526AZC CSB-MP517526AZC CSB-EP517526AZC-B	Recombinant Ajellomyces capsulatus Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP521025SXV CSB-EP521025SXV CSB-BP521025SXV CSB-MP521025SXV CSB-EP521025SXV-B	Recombinant Schizosaccharomyces pombe Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (idh1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)

Code	Product Name	Source
CSB-YP526076KBK CSB-EP526076KBK CSB-BP526076KBK CSB-MP526076KBK CSB-EP526076KBK-B	Recombinant Kluyveromyces lactis Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP725344PYX CSB-EP725344PYX CSB-BP725344PYX CSB-MP725344PYX CSB-EP725344PYX-B	Recombinant Pongo abelii Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP751079SH CSB-EP751079SH CSB-BP751079SH CSB-MP751079SH CSB-EP751079SH-B	Recombinant Sheep Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP850685DOA CSB-EP850685DOA CSB-BP850685DOA CSB-MP850685DOA CSB-EP850685DOA-B	Recombinant Arabidopsis thaliana Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IDH1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP893604BO CSB-EP893604BO CSB-BP893604BO CSB-MP893604BO CSB-EP893604BO-B	Recombinant Bovine Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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