IFIH1 is a human gene encoding melanoma differentiation-associated protein 5 (MDA5). This protein is a RIG-I-like receptor dsRNA helicase enzyme MDA5 is part of the RIG-I-like receptor (RLR) family, which also includes RIG-I and LGP2. it functions as innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking 2'-O-methylation at their 5' cap and long-dsRNA. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases

IFIH1 Antibodies

IFIH1 Antibodies for Homo sapiens (Human)

IFIH1 Proteins

IFIH1 Proteins for Mus musculus (Mouse)

IFIH1 Proteins for Homo sapiens (Human)


IFIH1 ELISA Kit for Homo sapiens (Human)


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