IGF2BP2, also known as insulin - like growth factor 2 mRNA - binding protein 2, is a well - studied protein. It has aliases such as IMP2. Functionally, IGF2BP2 binds to specific mRNAs, regulating their stability, localization, and translation. It is involved in the Wnt/β - catenin signaling pathway, which plays a vital role in cell proliferation and differentiation.
IGF2BP2 has been linked to several diseases, including diabetes and cancer. In diabetes, it affects glucose metabolism. In cancer, it promotes tumor growth and metastasis. Currently, research is ongoing to develop drugs that can target IGF2BP2, aiming to disrupt its function and provide new treatment options for related diseases.
IGF2BP2 Antibody (CSB-PA908724)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA908724(IGF2BP2 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA908724(IGF2BP2 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA908724(IGF2BP2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
Human Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2) ELISA kit (CSB-EL011091HU)
Validated Data
Code: CSB-EL011091HU
Size: 96T,5×96T,10×96T
Sensitivity: 31.25 pg/mL
Detection Range: 125 pg/mL-8000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following IGF2BP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IGF2BP2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA011091GA01HU | IGF2BP2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA006676 | IGF2BP2 Antibody | Human | WB, ELISA |
CSB-PA908724 | IGF2BP2 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA215752 | IGF2BP2 Antibody | Human,Mouse | ELISA,WB |
IGF2BP2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP897316HU CSB-EP897316HU CSB-BP897316HU CSB-MP897316HU CSB-EP897316HU-B |
Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF2BP2 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL011091HU | Human Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 31.25 pg/mL |