IL1R1

Interleukin-1 receptor type 1 is a protein in humans that is encoded by IL1R1 gene. Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

IL1R1 Antibodies

IL1R1 Antibodies for Homo sapiens (Human)

IL1R1 Proteins

IL1R1 Proteins for Homo sapiens (Human)

IL1R1 Proteins for Mus musculus (Mouse)

IL1R1 ELISA Kit

IL1R1 ELISA Kit for Homo sapiens (Human)

IL1R1 ELISA Kit for Mus musculus (Mouse)

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