KLK2, kallikrein-related peptidase 2, also known as human kallikrein 2 (hK2), is a secreted serine protease predominantly produced by prostatic epithelial cells. It exerts proteolytic activity alongside PSA and takes part in normal metabolic regulation within prostate tissues.
Upregulated KLK2 is detected prominently in prostate carcinoma. It serves as a circulating biomarker to distinguish benign prostate hyperplasia from malignancy and supports cancer cell invasion. Targeted antibodies and imaging probes against KLK2 are under clinical exploration for prostate cancer diagnosis and immunotherapeutic development.
Recombinant Human Kallikrein-2 (KLK2) (CSB-EP012453HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
KLK2 Antibody (CSB-PA012453LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA012453LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012453LA01HU at dilution of 1:100
The following KLK2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KLK2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA085005 | KLK2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA039286 | KLK2 Antibody | Human | ELISA,IHC |
| CSB-PA012453LA01HU | KLK2 Antibody | Human | ELISA, IHC |
| CSB-PA012453LC01HU | KLK2 Antibody, FITC conjugated | Human | |
| CSB-PA012453LD01HU | KLK2 Antibody, Biotin conjugated | Human | ELISA |
KLK2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-BP012453HU CSB-EP012453HU-B |
Recombinant Human Kallikrein-2 (KLK2) | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP012453HU | Recombinant Human Kallikrein-2 (KLK2) | E.coli |
| CSB-YP012453HU | Recombinant Human Kallikrein-2 (KLK2) | Yeast |
| CSB-EP012453HUg5 | Recombinant Human Kallikrein-2 (KLK2) | E.coli |
KLK2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-BP012453RA CSB-EP012453RA-B |
Recombinant Rat Tonin (Klk2) | Baculovirus In Vivo Biotinylation in E.coli |
KLK2 Proteins for Blarina brevicauda (Northern short-tailed shrew)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP685818BTI CSB-EP685818BTI CSB-BP685818BTI CSB-MP685818BTI CSB-EP685818BTI-B |
Recombinant Blarina brevicauda Blarinasin-2 (KLK2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KLK2 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13094h | Human Kallikrein 2(hK 2) ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/mL |