KLRC1, also known as CD161 or NKG2A, is a protein prominently present in the immune system, particularly within natural killer (NK) cells and a subset of cytotoxic T cells. Characterized by a type II membrane orientation and equipped with a C-type lectin domain, KLRC1 pairs with KLRD1, also known as CD94, to crucially recognize major histocompatibility complex (MHC) class I HLA-E molecules. This interaction is fundamental for the activation and cytotoxic capabilities of NK cells, underscoring KLRC1's vital role in immune responses, especially in the detection and elimination of cells that are tumorous or virus-infected.
KLRC1 Antibody (CSB-PA012466ESR1HU)
Validated Data
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA012466ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA012466ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA012466ESR1HU at dilution of 1:100
The following KLRC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KLRC1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA012466GA01HU | KLRC1 Antibody | Human | ELISA,WB,IHC |
CSB-PA012466ESR1HU | KLRC1 Antibody | Human | ELISA, IHC |
CSB-PA919911 | KLRC1 Antibody | Human | ELISA,WB |
CSB-PA005326 | KLRC1 Antibody | Human | WB, ELISA |
CSB-PA009651 | KLRC1 Antibody | Human | WB, ELISA |
CSB-PA073427 | KLRC1 Antibody | Human | ELISA,IHC |
CSB-PA911316 | KLRC1 Antibody | Human | ELISA,IHC |
KLRC1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP012466HU1 CSB-EP012466HU1 CSB-BP012466HU1 CSB-MP012466HU1 CSB-EP012466HU1-B |
Recombinant Human NKG2-A/NKG2-B type II integral membrane protein (KLRC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF012466HU | Recombinant Human NKG2-A/NKG2-B type II integral membrane protein (KLRC1) | in vitro E.coli expression system |
KLRC1 Proteins for Pan troglodytes (Chimpanzee)
Code | Product Name | Source |
---|---|---|
CSB-YP856823EQV CSB-EP856823EQV CSB-BP856823EQV CSB-MP856823EQV CSB-EP856823EQV-B |
Recombinant Pan troglodytes NKG2-A/NKG2-B type II integral membrane protein (KLRC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |